Enzymatica Q4: Important year ahead and an expected rights issue

Research Update

2024-02-19

07:00

Redeye provides an update in relation to Enzymatica’s Q4 2023 report. The report came in a bit under our expectations. Moreover, the company carries out a rights issue of SEK27.4m, which aligns with our estimate. Based on the report, we make some changes in our forecasts; however, the changes do not render an updated fair value range, including a base case of SEK6.

GM

Gustaf Meyer

Contents

Investment thesis

Q4 2023 review

Events after the reporting period

Estimate changes and outlook

Fair value range

Peer valuation

Quality Rating

Financials

Rating definitions

The team

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Q4 2023 review

The sales for Q4 came in at SEK15.8m (SEK16.6m), 13% under our sales estimate of SEK18.2m. This corresponds to a y/y decrease of -5%, where we learned from the report that the main reason for the declining sales is inadequate order intake from Enzymatica’s international partners. However, sales in Enzymatica’s own markets have been strong, growing 14% y/y in Q4 2023. Moreover, the gross margin for the quarter was 64% (66%), which was a bit higher than our estimate of 61%. Operating expenses amounted to SEK-23.9m (SEK-32.5m) compared to our OPEX estimate of SEK-19.4m, and EBIT came in at SEK-13.8m (SEK-21.6m), lower than our EBIT estimate of SEK-8.4m. The difference between our estimates and the reported results is mainly lower sales and a bit higher operating expenses on all line items.

Rights issue

Last week, Enzymatica announced it has decided to carry out a rights issue of SEK27.4m, with preferential rights for existing shareholders. The rights issue aims to secure the working capital needed for the operations and expansion in existing and new markets. Under the rights issue terms, one existing share in Enzymatica carries one subscription right, while 18 subscription rights entitle the holder to subscribe to one new share at the price of SEK3.0 per share. We also learned that the rights issue has been fully secured by the company’s three largest shareholders, the chairman, two members of the board, and Enzymatica’s CEO.

The subscription period runs between February 28, 2024, and March 13, 2024. The share capital will increase by SEK365,015 and the number of shares by 9,125,380, from 164,256,840 to 173,382,220, representing a dilution of approximately 5.6%.

Fair value range

Based on the report, we make some estimate changes; however, the changes do not significantly impact our fair value range. We update the number of shares and increase the cash position as a result of the upcoming fully-secured rights issue. However, as we had already anticipated a rights issue of SEK30m, the confirmed share issue does not affect our valuation. Concludingly, our fair value range remains with a base case of SEK6, a bull case of SEK13, and a bear case of SEK1.5.

Key financials

SEKm2021202220232024e2025e
Revenues57.248.950.982.8192.0
Revenue Growth-48.5%-14.5%4.0%62.6%132%
Gross Profit Margin58.3%58.1%62.6%58.5%55.2%
EBIT-45.2-68.2-48.1-40.610.5
EBIT Margin-79.0%-139%-94.4%-49.0%5.5%

Source: Redeye research (forecasts)

Investment thesis

Case

Global launch

Enzymatica’s product, ColdZyme, is a medical device that treats and alleviates the common cold and shortens its duration. The company is responsible for ColdZyme sales in the Swedish market and has, with distributors, launched the device in more than 30 markets worldwide. It aims to expand this to launches into another 30 markets over the next three years and its global rollout should expand its sales significantly in the coming years. As its distributors cover the launch expenses, we argue the product can generate significant sales for Enzymatica while not increasing the company’s costs significantly. We expect an EBIT margin of 25% at the end of our forecast period (2036e).

Evidence

Well-known distributors and solid track record

We highlight Enzymatica’s distribution agreements as these are with well-known players with expansive global networks, which we consider essential for the geographical expansion of ColdZyme. These partners are responsible for the majority of markets in which ColdZyme has been or will be launched. Statista values the Swedish cold and cough market at SEK1.3bn, and we assume ColdZyme has a current market share of around 3-5%. The establishment of this market in Sweden convinces us of the apparent demand for the product. Moreover, according to a market study, ColdZyme is Swedish pharmacists’ most recommended common cold product. We argue ColdZyme can establish itself in larger markets where the competition is similar to Sweden, while its distributors’ activity creates further conviction in these expectations.

Challenge

Regulatory changes

Regulatory requirements often change and can differ between markets. In 2017, STADA launched ColdZyme in Germany, where it was initially a success. However, the product was taken off the market due to local and national marketing requirements that demanded clinical data. We argue it is crucial for Enzymatica to continue performing studies on ColdZyme, as additional data can be useful to support future regulatory changes and new territories.

Challenge

Finding the right partners

As Enzymatica’s business model is reliant on the distribution partners, we highlight the importance of finding the right partners in markets where regulatory requirements are dynamic and ColdZyme has not yet been launched. Enzymatica does not have distribution agreements in much of Asia or in the US, which are large markets with considerable future potential. The choice of distribution partner is crucial for future success and so we regard this as a possible challenge.

Valuation

Great long-term potential

We believe Enzymatica’s current share price level does not reflect the potential in ColdZyme’s geographical expansion. As Enzymatica continues its global launch of ColdZyme, we believe quarterly reports and new market launches will represent potential triggers for the share that we expect can close the gap to our base case within the next c12 months.

Q4 2023 review

The sales for Q4 came in at SEK15.8m (SEK16.6m), 13% under our sales estimate of SEK18.2m. This corresponds to a y/y decrease of -5%, where we learned from the report that the main reason for the declining sales is inadequate order intake from Enzymatica’s international partners. However, sales in Enzymatica’s own markets have been strong, growing 14% y/y in Q4 2023. Moreover, the gross margin for the quarter was 64% (66%), which was a bit higher than our estimate of 61%. Operating expenses amounted to SEK-23.9m (SEK-32.5m) compared to our OPEX estimate of SEK-19.4m, and EBIT came in at SEK-13.8m (SEK-21.6m), lower than our EBIT estimate of SEK-8.4m. The difference between our estimates and the reported results is mainly lower sales and a bit higher operating expenses on all line items.

The cash flow from operating activities was SEK-2.6m (SEK-27.7m), and by the end of the quarter, the cash and cash equivalents amounted to SEK8.4m (plus SEK1.5m in unutilized credit facilities). However, we also learned that Enzymatica carries out a fully secured rights issue of SEK27.4m (before issue-related costs) with a subscription period between February 28, 2024, and March 13, 2024. After the issue, we estimate the cash position will be around SEK25-30m. We believe the updated cash position could be sufficient to cover business activities during 2024; however, that considers increasing sales. We had already included a rights issue in our model (SEK30m). Therefore, we were not surprised by the announcement, and the dilution effect was already included in our valuation of Enzymatica.

Overall, the report came in a bit under our expectations; however, we are positive about the sales growth in Enzymatica’s own markets. We learned from the report that several partners have indicated that they await the MDR certification of ColdZyme before order intake can increase. Enzymatica expects the certification during the spring of 2024. Moreover, positive study data will be important for an increased order intake by Enzymatica’s partners. The company provided solid data during the second half of 2023, and we learned from the report that the final results from the double-blind and placebo-controlled clinical study at the University of Kent will be reported during Q2 2024. We argue positive results could act as a solid trigger for the share.

Actuals vs estimates

SEKmQ4 ’23Q4 ’23eDiff
Revenues15.818.2(13.0%)
Gross Profit Margin64.2%60.5%
Operating Expenses23.919.423.3%
EBIT-13.8-8.4(64.0%)

Source: Redeye research

Events after the reporting period

Last week, Enzymatica announced it has decided to carry out a rights issue of SEK27.4m, with preferential rights for existing shareholders. The rights issue aims to secure the working capital needed for the operations and expansion in existing and new markets. Under the rights issue terms, one existing share in Enzymatica carries one subscription right, while 18 subscription rights entitle the holder to subscribe to one new share at the price of SEK3.0 per share. We also learned that the rights issue has been fully secured by the company’s three largest shareholders, the chairman, two members of the board, and Enzymatica’s CEO.

The subscription period runs between February 28, 2024, and March 13, 2024. The share capital will increase by SEK365,015 and the number of shares by 9,125,380, from 164,256,840 to 173,382,220, representing a dilution of approximately 5.6%.

Estimate changes and outlook

As mentioned, the report came in a bit under our expectations. We have chosen to make some changes to our estimates for 2024e-2025e. Firstly, we decrease our 2024e sales estimate from SEK94.8m to SEK82.8m, mainly as we expect lower partner sales during the year than previously anticipated (primarily during Q1 2024e). Secondly, we decrease our sales estimate for the full year 2025e from SEK217.3m to SEK192.0m due to a more cautious view of future partner sales. Lastly, we make a minor increase in administrative costs for 2024e. However, these changes do not significantly impact our valuation of Enzymatica.

Estimate changes 2024e-2025e

SEKm2024eOldChange2025eOldChange
Revenues82.894.8(12.7%)192.0217.3(11.6%)
Operating Expenses89.087.12.2%95.595.50.0%

Source: Redeye research (forecasts)

We continue to expect a rise in sales during 2024e, estimating sales of SEK82.8m. This increase is mainly driven by continued growth in Enzymatica’s own markets and that an MDR certification and positive study data will increase sales in international markets. Moreover, we look forward to more study data. Firstly, as mentioned, positive data will be important for upcoming order flow from Enzymatica’s distributors. Secondly, positive study data has previously been a major trigger for the share, and we continue to expect positive data and rising sales as two major catalysts to decrease the gap between current share price levels and our base case.

Income statements 2023-2025e (SEKm)
FY 2023Q1 24eQ2 24eQ3 24eQ4 24eFY 2024eFY 2025e
Net sales50.916.611.623.231.582.8192.0
Growth y/y4%27%32%75%99%63%132%
Gross profit31.910.16.713.418.248.4106.0
Gross margin63%61%58%58%58%58%55%
Selling expenses-28.4-8.0-4.6-8.3-9.9-30.9-32.6
Administrative expenses-39.4-10.7-10.7-10.8-10.9-43.1-43.4
R&D expenses-15.3-4.0-2.3-3.7-6.1-16.1-21.7
Other op.Income/expenses3.20.30.30.30.31.22.2
OPEX-79.9-22.5-17.3-22.6-26.6-89.0-95.5
EBIT-48.1-12.4-10.6-9.1-8.4-40.610.5
EBIT margin-94%-75%-91%-39%-27%-49%5%
Source: Redeye research (forecasts)

Fair value range

As mentioned, our estimate changes do not significantly impact our fair value range. We update the number of shares and increase the cash position as a result of the upcoming fully-secured rights issue. However, as we had already anticipated a rights issue of SEK30m, the confirmed share issue does not affect our valuation. Concludingly, our fair value range remains with a base case of SEK6, a bull case of SEK13, and a bear case of SEK1.5.

Peer valuation

In addition to our DCF valuation, we offer a peer group analysis that compares Enzymatica with other medtech companies in the Nordic region. We consider EV/Sales the best measurement, as Enzymatica is not currently profitable.

CompanyEV (SEKm)20232024e2025e
Acarix12211.1x1.0x0.6x
Bactiguard263011.8x12.2x11.1x
Dignitana1531.7x1.3x0.9x
Midsona15460.4x0.4x0.4x
Moberg pharma163162.6x32.5x3.9x
Sedana Medical14329.3x7.8x6.3x
Stille7032.4x1.4xna
Xvivo Perfusion756812.7x9.4x6.9x
Median106810.2x4.6x3.9x
Enzymatica4929.7x5.9x2.6x
Source: Factset, Redeye research

When comparing Enzymatica to other medtech companies, we can observe that the Enzymatica share currently trades at 9.7x times its 2023 sales and 5.9x its 2024e sales. As can be observed, Enzymatica is currently valued relatively in line with the selected peers. We highlight two things from the peer valuation. Firstly, one should notice the difference between Enzymatica and the selected peers, and secondly, in general, life sciences companies’ valuations have decreased significantly during 2023; however, Enzymatica’s valuation has been relatively stable. This indicates that the market currently has high expectations of the company.

Quality Rating

People: 4

The management team is solid and brings extensive experience from commercial and growth companies. In addition, there is strong sector expertise. The board brings extensive experience in life science and growth companies. It is also positive that the largest shareholder, Mats K Andersson, is one of the board members.

Business: 3

The business model is appealing, with a solid strategy to become profitable in the future. Enzymatica has already established ColdZyme in Sweden, creating conviction in a successful global expansion. We are positive about the company’s well-known distribution partners as they will be crucial for Enzymatica’s future growth.

Financials: 1

Enzymatica has a few years ahead of it before it turns profitable. Through its global expansion of ColdZyme, however, we believe the company will become profitable in 2025.

Financials

Income statement
SEKm2021202220232024e2025e
Revenues57.248.950.982.8192.0
Cost of Revenue23.920.519.034.486.0
Operating Expenses78.696.779.989.095.5
EBITDA-45.2-68.2-48.1-40.610.5
Depreciation0.000.005.04.25.4
Amortizations-3.27.71.44.25.4
EBIT-45.2-68.2-48.1-40.610.5
Shares in Associates0.000.000.000.000.00
Interest Expenses1.51.32.31.00.00
Net Financial Items-0.94-0.53-1.7-1.00.00
EBT-46.2-68.7-49.7-41.610.5
Income Tax Expenses-0.31-0.090.010.000.00
Net Income-45.9-68.7-49.7-41.610.5
Balance sheet
Assets
Non-current assets
SEKm2021202220232024e2025e
Property, Plant and Equipment (Net)15.216.416.514.012.4
Goodwill59.70.000.000.000.00
Intangible Assets2.070.868.365.864.2
Right-of-Use Assets0.000.000.000.000.00
Other Non-Current Assets14.810.79.99.99.9
Total Non-Current Assets91.698.094.789.786.5
Current assets
SEKm2021202220232024e2025e
Inventories12.411.511.58.319.2
Accounts Receivable20.714.211.316.628.8
Other Current Assets0.000.000.000.000.00
Cash Equivalents32.250.78.4-5.05.4
Total Current Assets65.476.431.219.853.4
Total Assets157.0174.4125.9109.5139.9
Equity and Liabilities
Equity
SEKm2021202220232024e2025e
Non Controlling Interest0.000.000.000.000.00
Shareholder's Equity125.0126.376.661.171.6
Non-current liabilities
SEKm2021202220232024e2025e
Long Term Debt1.121.124.924.924.9
Long Term Lease Liabilities0.000.000.000.000.00
Other Long Term Liabilities0.000.000.000.000.00
Total Non-Current Liabilities1.121.124.924.924.9
Current liabilities
SEKm2021202220232024e2025e
Short Term Debt1.51.21.21.21.2
Short Term Lease Liabilities0.000.000.000.000.00
Accounts Payable7.66.77.49.919.2
Other Current Liabilities21.819.115.812.423.0
Total Current Liabilities30.927.024.423.643.5
Total Liabilities and Equity157.0174.4125.9109.5139.9
Cash flow
SEKm2021202220232024e2025e
Operating Cash Flow-35.2-65.4-40.3-36.118.1
Investing Cash Flow-6.1-3.7-0.73-3.3-7.7
Financing Cash Flow49.588.2-1.426.00.00

Source: Redeye research (forecasts)

Rating definitions

The team

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Contents

Investment thesis

Q4 2023 review

Events after the reporting period

Estimate changes and outlook

Fair value range

Peer valuation

Quality Rating

Financials

Rating definitions

The team

Download article